Tuesday, April 30, 2024

Unique Deck Shapes and Designs Trex

trex deck design ideas

Trex decking supplies cost an average of $8.25 per square foot, while decking labor costs $7.52 per square foot. You will adore how this modern take on a lawn pond blends in with its environment, breaking up the length of decking and preventing it from taking over the space. All you’ll need is an old sheet draped from a neighboring fence or wall, as well as the greatest outdoor projector.

Take a peek at the view from the deck.

Parade of Homes 2022: ‘Midnight’ by Stone Hammer Homes (photos) - syracuse.com

Parade of Homes 2022: ‘Midnight’ by Stone Hammer Homes (photos).

Posted: Thu, 13 Oct 2022 07:00:00 GMT [source]

Deep reds, orange, and patterns accessorize the furniture with light cushions. A custom staircase is made striking by changing it the color to a very light – almost white – color. The greens are mixed and matched to add a more natural feel to this urban oasis. The upper deck has a drainage system installed to redirect water away from the deck to the downspouts on the support posts.

Color Selector

Notice the stair risers were built using a different color. That option could have been used here, as there’s an edge that runs parallel with the open steps. You’ll spend more on a couple of coats of wood stain, and you’ll also have to keep an eye on your stair stringer as it can wear out before it becomes noticeable at a glance. When it comes to durability, Trex decks are the smart choice.

Decking surrounding a pool that is non-slip

A couple of attractive Adirondack chairs and a few plants make for a comfortable spot that will soon become your favorite room in the house. Don’t overlook an opportunity to build a rooftop deck if your home allows. Tucked away off a master bedroom, hallway, or some secret attic location, a rooftop deck can be a fun spot to spend time with friends or simply hide away with your favourite book. Think outside the box - and rectangle - with curved rails and decking. Add a special touch, like this circular built-in seating made from Trex deck boards, and you have the perfect spot for entertaining. Post cap lights on the Classic White Transcend composite posts and riser lights along the stairs and fascia allow this family to enjoy their deck long after the sun goes down.

trex deck design ideas

Unique Deck Shapes and Designs

Bear in mind, though, that Trex’s greater grades are more pricey than Timbertech’s lower-tiered grades, so be certain you’re evaluating apples to apples. In most town gardens, there is typically unused space at the far end that people never use. If you live in a city, you may be fortunate enough to have your own personal roof patio.

Get Started With Designing Your Backyard Deck Today!

Trex offers a variety of fencing and privacy screen options to compliment your deck. Plenty of composite fencing ideas are out there, making privacy a part of your outdoor design rather than an afterthought. If you’re looking for a modest garden design to help your space feel larger, finish your decking in a bright color that reflects light for a space-expanding impression. Create space for planting within your overall design to soften the lines of your decking ideas. Spikes of architectural greenery, as well as blossoms, pour over onto the terrace from the split-level feature’s beds.

Creative Lattice Fence Ideas For Your Backyard

Here, a second, complementary tone has been used around the counters for a subtle style statement, complete with recessed spotlights for illuminating the scene come nightfall. Building a deck around a beloved tree can provide a unique space to relax, unwind and entertain. With some due diligence, you can save that favourite tree and build your space around it. It does require some extra planning but offers a number of benefits, including enjoying a more natural aesthetic and promoting an environmentally friendly space. I have collaborated with Trex to bring you these design ideas for your back yard! It is the first company I have teamed up with my blog because I love their product.

Combine a composite deck with a matching pergola

The garden was always a big part of Holly's life growing up, as was the surrounding New Forest where she lived. Her appreciation for the great outdoors has only grown since then. She's been an allotment keeper, a professional gardener, and a botanical illustrator – plants are her passion. Composite decking is perfect for contemporary courtyards like this – it's much easier to look after than a lawn and will always look good.

trex deck design ideas

Because wood decking needs quality assurance in any case, all you have to do is use a brightening color of your choice instead of re-treating it with a wood preservative. However, if you add a deck to your home, it may become a destination for your outdoor dining options or simply a place to rest. Because this deck is somewhat elevated, it becomes even more of a focus point. The curved line brings visual appeal, and choosing a color that is subtly different from the decking itself creates a pleasing contrast.

A layout like this could be just the thing if you’re looking for a creative option to deck railing ideas. It not only defines the perimeter in aesthetic, but it also serves as a large seating area, which is ideal if you like to host garden parties. Establishing an outdoor theater is a certain way to create memorable nights with friends and family, and a robust deck will serve as a firm foundation. If you really want to go all the way out with your decking ideas, a style like this could be the way to go.

20 Simple Outdoor Stairs Design Ideas For House 2024 - Styles At Life

20 Simple Outdoor Stairs Design Ideas For House 2024.

Posted: Thu, 06 Jul 2023 09:29:32 GMT [source]

Adding some pillows and throws that play off the surrounding environment make for a cohesive aesthetic that feels welcoming and inviting. Add pops of color that complement your backyard, accessories that make you feel good, and groupings of potted plants that add visual appeal. It takes a little more creativity to plan a deck with curves, but the payoff is spectacular.

Then, for a refined look, match your deck with basic garden furniture designs accentuated with splashes of colored pillows. This elegant deck is a terrific place to unwind away from the main home, and it blends in nicely with the garden building’s facade. Also note the matching planter, which adds to the overall feeling of coherence. If you don’t want to, you don’t have to use natural wood hues on your deck. Choosing a dark color for an outdoor location may provide a dramatic touch. Incorporating additional deck lighting ideas is one way to quickly add attractiveness to your outdoor dining area.

They’ll also work in cottage-style gardens if you pair them with vintage-looking furnishings. You may also like how the chairs’ colors and forms have been blended here to create a casual eclectic vibe. Black and gray have a modern feel to them, but they’re not only for contemporary garden ideas. The light color serves to lighten the area while still blending in with the surrounding walls. Throws and cushions will add extra coziness, and a string of lights suspended from the ceiling and a warm chiminea nearby will complete the inviting scene.

Composite decking doesn’t sound any more environmentally friendly than wood decking until you factor in the use of reclaimed materials. A 500-square foot outdoor deck made from Trex boards contains 140,000 recycled plastic bags. Picking out all of the little extras to personalize the deck to your taste. You'll need deck furniture if you plan to lounge around and entertain friends, family, and loved ones. Outdoor throw pillows and planters can beautify your space.

Social media sounds off on Georgia football program following 2024 NFL Draft first round

dawg house

And the lyrics are worse, as Ye spends the first half of the verse rapping about himself before firing off a few half-baked shots about Lucian Grainge, J. Cole, how he “can’t even think of a Drake line” (which is a lie). This remix falls in line with many of the lackluster verses that Ye has dropped recently, and it’s clear that he didn’t have much to add to this rap war, besides reigniting his long-running feud with Drake. As pet parents, we’d like to think that we have every solution for behavior issues, like how to stop a dog from peeing in his crate.

Facilities spotlight: work requests

There are several actions that could trigger this block including submitting a certain word or phrase, a SQL command or malformed data. Firefighters set up tanker shuttles to attempt to ease the impact on the municipal water supply. As dawn broke Saturday morning, flames and smoke continued to billow out of the hollowed out walls of the massive structure, with four ladder trucks pouring water onto the wreckage. DETROIT, Mich. — University of Georgia TE Brock Bowers is the first Bulldog to be drafted in the 2024 NFL Draft. Physically present in AZ/CO/CT/IL/IN/IA/KS/KY/LA(select parishes)/MA/MD/ME/MI/NC/NH/NJ/NY/OH/OR/PA/TN/VA/VT/WV/WY only.

Pallet Dog House Plan

Drake is such an indomitable force in rap that it takes a whole army of foes to join forces and make a coordinated effort just to attack him, and even then, he still finds a way to fire back against them all. He transforms the original Metro-produced beat by adding a choir of Inter Milan hooligans, in the same way that he did on his No. 1 song “Carnival,” which makes it feel like it could have soundtracked a blockbuster movie trailer. But sadly, it’s less like Tarantino’s The Hateful Eight and more like Marvel’s Ant-Man 3.

What to look for in a dog house

Country music star Chris Young arrested at Nashville bar - WECT

Country music star Chris Young arrested at Nashville bar.

Posted: Tue, 23 Jan 2024 08:00:00 GMT [source]

Rappers like Rick Ross and Ye have answered the call, while Drake has been fighting back with his own responses (and AI?) to even the score. As we wait for more shots to land in the near future, here is a ranking of all of the direct diss tracks (not counting some of the more subliminal verses on We Still Don’t Like You) that have come out of this rap war so far. Before using these free dog house plans to build your dog's dream home, make sure that it will be the right fit for the size of your full-grown dog. Some of these plans can even be customized to fit any size of dog, so be sure to look for instructions within the plans for that. These 14 free DIY dog house plans will make sure that your dog has a safe haven from the weather and you can take pride that you built it just for them.

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Hermiston boys, girls wrestle to victory against Chiawana - East Oregonian

Hermiston boys, girls wrestle to victory against Chiawana.

Posted: Fri, 12 Jan 2024 08:00:00 GMT [source]

Guests can also experience Mouse House, a dining truck serving specialty grilled cheeses within Dawg House. Placing a high-quality dog bed in your dog’s house will keep them comfortable regardless of the weather. Thick, flannel beds are a great option during the winter months, and breathable foam is a good choice as the temperature rises. Some dog beds even have a layer of cooling gel to ensure your pup doesn’t overheat in hot weather.

Some dog houses have doors on them, so if you want the most versatility, look for a dog house with a removable door to maximize air flow during hotter months. With an original location on Nashville’s Music Row, Dawg House Saloon is a classic Nashville sports bar perfect for those who love music and watching the game. Situated adjacent to the Resorts World Las Vegas sportsbook, the venue features live music and dancing, an array of draft beers, creative cocktails, and classic American pub fare with a Southern twist.

dawg house

When you and you dog are out and about, your dog's collar is an important part of keeping them safe. It holds their tags, which has vital info that can help you reunite if your dog gets lost, is a convenient place to hold onto if the leash breaks, and it lets other people know that your dog isn't a stray if they get lost. Dr. Bartley Harrison is a veterinarian with more than 15 years of professional veterinary experience treating dogs, cats, rabbits, ferrets, birds, and small mammals, with a specific focus on Emergency Medicine. Dr. Harrison is part of The Spruce Pets’ veterinary review board. It has the nostalgic feel to it, but something like this is also timeless and feels like you’re wearing something special.

Residence Hall Checkout Deadline For Residents Not Participating In Commencement

Are you looking for a dog house that will hold up to rainy weather without leaking? Plastic dog houses are lightweight, reasonably priced, and they come in a wide variety of unique designs. You can find plastic dog houses shaped like castles, miniature homes, and barns. Some dog houses even have built-in food and water bowls, so your dog won’t have to leave the comfort of their home for long to have a bite to eat. A good dog house will provide enough space for your dog to turn around comfortably. If you live in a warm, sunny climate with mild to moderate winters, you should ensure your dog has plenty of space inside of their home.

Browns fans are used to seeing the classic STARTER satin jackets, but today, for the first time ever, they have partnered with HOMAGE to release the first ever STARTER windbreakers! Bulldog Battle is a monthly competition for residents to show off their rooms leading to the annual Room of the Year vote in April. Log onto The Dawg House portal to register for housing, request a room change or manage your profile.

Your buddy can’t exactly tell you why he pees in the crate when you’re not home, though, and you can't always catch him in the act — so it can be tricky.Luckily, with a keen eye and a few trial runs, you’ll figure out the problem in no time. You can always enlist your family, vet, or local doggie daycare to keep an eye out, too, but it’s up to you to make the necessary changes to change the behavior. Anything from a more consistent routine to a new treat-dispensing toy could be the difference between cleaning up a puddle or coming home to a happy pup.Here’s how to stop your dog from peeing in his crate. According to PetMD, a dog house is a perfect safe haven for fearful dogs. Keeping your dog out of direct sunlight during the summer is also beneficial, as dogs can easily overheat, and dogs with lighter-colored coats are at an increased risk of sunburn. Since Kendrick’s explosive verse on “Like That” acted as a signal flare for anybody who has problems with Drake to step forward and get at him.

dawg house

This will help your dog stay cool during those hot summer months. Traditional dog houses serve their purpose, but they’re nothing special to look at. Fortunately, there’s no need for your dog to have a dull, run-of-the-mill dog house anymore. Today’s dog houses are designed to suit your dog’s size as well as your climate, ensuring your pooch stays perfectly comfortable all year long.

Let your unique dog house ideas come to fruition so your furry friend can relax in style. That way, he or she can chill in a fun, interesting space that will make your backyard infinitely more stylish — and keep your dog happy and comfortable in their home no matter the season. Yes, J. Cole loses points for apologizing for his diss at Kendrick Lamar and taking “7 Minute Drill” off of streaming. But even though Cole’s heart was never in the fight in the first place, his response to Kendrick’s “Like That” verse still out-paces some of the AI raps and self-indulging remixes that have followed it. There have already been half a dozen diss songs in the rap war between Drake, Kendrick Lamar, and more. We’re the only spot on the Las Vegas Strip where you’ll find a variety of live music and dancing with no cover charge!

Chances are good you’ll want to show off a unique, stylish dog house, but you should always keep your dog’s comfort in mind while doing so. Placing your dog house in the shade during the summer will help keep your dog cool, while moving it to the sunniest location in your yard will ensure maximum warmth during the winter months. If your dog is prone to overheating — or you live in a hot climate — avoid heavier materials that trap in heat. A roof made from engineered wood is a better fit than a shingled roof, as it won’t retain as much heat as dense shingles.

According to HOMAGE, this is a limited release and they don’t expect them to last long. Click here to purchase one, and let us know which one you decided to get. Even if it’s not for you, they would make an awesome birthday or early Christmas gift to stock up on for any family, friend, or colleague. Enjoy a variety of libations from one of our eclectic bars and lounges. This website is using a security service to protect itself from online attacks.

Monday, April 29, 2024

Free Online Postcard Maker Create Pretty Postcards

postcard design template

At Edit.org, we publish a new and modern collection of postcard templates. With simple clicks and without using Photoshop, you will be able to create high quality printable postcards in seconds. Change the color, include your store logo and contact details and change the texts if required.

Mother's Day Postcards Slides

1.Open Fotor website, click “Create a design” button on the homepage, and choose postcard layout to start designing your postcard. Watch your words and phrases transform into beautiful images. Before you select the "standard size", consider the content you want to include and your company’s branding strategy, then select the postcard sizing that's the best fit. Write your recipient’s name and address (street address, area code, state and country) on the right side of the postcard. Add new text boxes and graphic elements, change the layout, or even start from scratch with our easy drag-and-drop editor.

How Much Does Direct Mail Marketing Cost? - PostGrid

How Much Does Direct Mail Marketing Cost?.

Posted: Mon, 01 Apr 2024 07:00:00 GMT [source]

How to make your own postcard online

The standard size for postcards is typically between 3 to 4 inches in height and 5 to 6 inches in length. This compact size is ideal for conveying short and sweet messages. If you want to put in longer messages and have more design flexibility, go for sizes like 4 x 9 inches, 5.5 x 8 inches, or 6 x 11 inches. With our postcard creator, you can easily customize the size of your artboard to suit your preferences. Pixlr's Postcard Maker provides a diverse selection of customizable templates suitable for various occasions. Whether you're sending postcards to loved ones or promoting your business, our templates make it effortless to craft attention-grabbing designs.

Create an unforgettable postcard with our powerful postcard maker tool

Signed, sealed, delivered — PsPrint's postcard design templates are yours. If you need quick postcard printing, then you’ve landed at the right place. In PsPrint’s easy-to-personalize postcard design template gallery, you can shop for a postcard design template and then customize it yourself. Your postcard will be a one-of-a-kind design that will be sure to stand out.

Stick the stamp on the top right corner of your postcard, which is the standard placement for stamps. You can buy a stamp at the post office, bank, gas station, supermarket, etc. No need to find design materials across platforms, and worry about any copyright issues.

postcard design template

From sophisticated and chic styles to humorous and colorful designs. Try a quick search through our library of printable postcard templates. You're sure to find the perfect postcard template for your taste and advertising communication needs. Get access to hundreds of professionally-designed postcard templates, high-quality stock photos, icons, charts, illustrations, and data visualization widgets to use. Stay in touch with family and friends, customers and colleagues, and more by creating fully customized postcards to send snail mail style. Create invitations, send out discounts to VIP customers, share recent family photos and more.

Slap a stamp on your postcard and drop it in the mailbox. Explore Fotor’s wide range of postcard templates to find a template that matches your needs. You can also type specific keywords on the search bar to narrow down the search. So even if you are not a designer, you can quickly create great custom postcards.

postcard design template

If you prefer a more personal approach, have your postcard printed with Kittl and hand-deliver it to your loved ones, or send it through the mail. Pixlr's Postcard Maker provides a selection of customizable templates that allow you to create unique postcards. Utilize the straightforward drag-and-drop interface to incorporate your personal photos, text, and graphics, ensuring your postcards are visually captivating. When designed well and targeted to the right people, postcards are a very effective means of marketing any local business.

Our free postcard templates and software are free to use. Nonetheless, some special templates require a small monthly fee (you can enjoy them by becoming a premium or business user). With Drawtify’s extensive online resources and high-quality editable postcard templates, anyone can get a charming custom postcard in minutes. Excitingly, Drawtify is a powerful online free postcard maker.

Choose from over a million stock photos, icons, illustrations, characters, lines, shapes and more to create an enticing and easy-to-browse postcard design. With Drawtify’s online free postcard maker, you can create engaging postcards in just a few minutes. When you exert unlimited creativity, you will get more charming postcards than the following postcard templates. Send your beautifully crafted postcards virtually via email, delivering a delightful surprise directly to your relatives or customers’ inbox. This adds a layer of modernity to the timeless charm of postcard sentiments, offering a delightful surprise that transcends geographical distances and instantaneously brings smiles to faces.

Postcards are a crucial marketing tool and can be used to attract new clients or give a friendly reminder of services to existing ones. You can personalize every element, including text, images, colors, and more, to align with your unique style or branding. Choose one of our premade customizable postcard templates to help you create custom postcards for your audience.

No matter how many templates are selected and how many design tasks are created. No matter how many images and design elements are used or uploaded in the design. The beauty lies in the details – tailor the layout of your postcard to your liking, choosing from an array of design options that suit your personality or the mood you want to convey.

Your CTA could be an invitation to visit your new location, participate in a sale, utilize valuable coupons, join a rewards program, attend an event, or call for a free consultation. Browse our catalog to find a postcard template that meets your needs. Gather together your high-quality images, original content, and an understanding of your company’s branding strategy, then open your chosen template in our online editor. Share your life and adventures with family and friends by creating and sharing your own custom postcards. Make postcards that allow your photos to shine, print them out and mail them to everyone you know.

Stay in touch with those who matter most by quickly putting together a beautiful and thoughtful postcard design. A postcard is a card with pictures and text that can be sent directly without an envelope. Its form is simple, but only charming postcards can attract people’s attention. Therefore, by using a powerful and free postcard maker, creating beautiful customized postcards online is your best choice.

Computer-Aided Drug Design Methods An update PMC

computer-aided drug design

This includes, but is not limited to, Aliskiren, Boceprevir, Captopril, Dorzolamide, Nolatrexed, Oseltamivir, Rupintrivir, Saquinavir and Zanamivir [2]. 5In the ligand optimization stage of CADD, as only a few compounds are under consideration, accuracy rather than computational efficiency is usually pursued. It uses all-atom explicit-solvent MD simulations that include small organic solutes, such as propane, methanol and others, to identify 3D functional-group binding patterns on the target.

Computational approaches to drug design

While FEP and molecular mechanics (MM) with Poisson–Boltzmann (PB) and surface area solvation (MM/PBSA) as well as MM/generalized-Born SA (GBSA) methods (107) do account desolvation, these are computational demanding approaches that limits their utility in CADD. A novel method designed to overcome this drawback is the SILCS-MC (19) docking method put forward by our laboratory. This takes advantage of the use of GCMC/MD simulations of the protein in aqueous solution with selected organic solutes to precompute the GFE FragMaps that are free energy functional group affinity patterns that encompass the entire protein and account for protein flexibility and desolvation contributions (108–110).

Challenges of gigascale screening

This technique uses a known active compound as a query compound to find similar compounds and then rank compounds identified in a database. Based on this belief, structurally similar molecules exhibit similar biological activities and physicochemical properties. Numerical descriptors are applied and similarity coefficient is defined to quantify the degree of similarity (similarity/ dissimilarity). A number of coefficients are applied in similarity searching with different fingerprint molecular databases (Cosine, Euclidian distance, Forbes, Tanimoto coefficients etc.). 3Protonation states of titratable residues at the targeted binding site and in the ligand being studied are quite important when setting up the CADD calculations.

AI in Drug Discovery: Trust, but Verify - Genetic Engineering & Biotechnology News

AI in Drug Discovery: Trust, but Verify.

Posted: Thu, 11 Jan 2024 08:00:00 GMT [source]

Fundamental steps used in pharmacophore modeling

computer-aided drug design

In the 1990’s, a large number of developments were undertaken using combinatorial and high-throughput screening technologies, which accelerated drug discovery [13-15]. These technologies were widely adopted because they enabled the rapid synthesis and screening of large libraries, but unfortunately, no significant success was achieved and little progress toward the development of new molecular entities was made [16, 17]. Dr. Scott R. Lokey is a Professor of Chemistry in the Department of Chemistry and Biochemistry at the University of California, Santa Cruz. His research group focuses on the relationship between molecular structure and drug-like properties, especially cell permeability. Professor Lokey is also the director of the UCSC Chemical Screening Center, a high-throughput screening facility dedicated to early stage lead discovery, and is co-founder of Circle Pharma, a biotech startup focusing on the discovery of cyclic peptide inhibitors against intracellular targets. Any lead compound can be modified structurally and maintain its physiochemical properties, thermodynamic, pharmacokinetic parameters, and toxicity (Jogensen, 2009).

Aurigene Pharmaceutical Services Ltd. introduces Aurigene.AI™, an artificial intelligence (AI) and machine learning ... - Yahoo Finance

Aurigene Pharmaceutical Services Ltd. introduces Aurigene.AI™, an artificial intelligence (AI) and machine learning ....

Posted: Wed, 03 Apr 2024 07:00:00 GMT [source]

Artificial Intelligence For Drug Development and Discovery Market 2022

The existing modern drug discovery implies the knowledge of genomics, bioinformatics, computational chemistry, and combinatorial chemistry for virtual screening, HTS, Lenovo ligands. However, the concept of LBDD relies mostly on drug planning, which develops a simple drug molecule, a 3D through trial and error methods that improves the overall biological activity of the compound. Although bioinformatics and molecular dynamics approaches can help to detect and analyse allosteric and cryptic pockets133, computational tools alone are often insufficient to support ligand discovery for such challenging sites. The cryptic and shallow pockets, however, have been rather successfully handled by fragment-based drug discovery approaches, which start with experimental screening for the binding of small fragments.

Ligand-Based Drug Design

In collaborative studies with the Wilks lab, we have successfully applied CADD techniques to identify inhibitors of the bacterial heme oxygenases from Pseudomonas aeruginosa and Neisseria meningitides, thereby confirming the potential role of heme oxygenases as a novel antimicrobial targets (13, 14). Computational binding site identification methods can be used to exploit novel, druggable sites on new protein targets for potential therapeutic development (113). For antibiotics development, such methods can be employed to search for putative allosteric sites as alternatives to the active or orthosteric sites on bacterial proteins to overcome drug resistance issues (114).

Other parameters like kinetics include thermodynamics, pharmacodynamics along with higher improvement in ADMET properties have also to be considered. Unfortunately, CADD suffers from cognitive dissonance (bias to seek consonance) and also sloppy research that results from the lack of proper training. The utility of the SSFEP approach is that the ΔΔG values for many modifications may be rapidly evaluated as the same trajectories from the original MD simulations of the hit compound are used in each case. This approach may be of use during the fine tuning of ligand affinity or specificity for a target or as required to improve physiochemical and pharmacokinetic properties without significantly altering desirable properties such as affinity. Docking involves posing a compound in the putative binding site on the target in an optimal way defined by a scoring function in combination with a conformational sampling method (78). Various docking programs are available that differ based on the scoring function used to describe the interaction between small molecule and the target and the conformational sampling method used to generate the binding poses of the ligand on the protein.

1. Structure-based Drug Design (SBDD)

Computer-aided drug design has helped to expedite the drug discovery and development process by minimizing the cost and time. In this review article, we highlight two important categories of computer-aided drug design (CADD), viz., the ligand-based as well as structured-based drug discovery. Various molecular modeling techniques involved in structure-based drug design are molecular docking and molecular dynamic simulation, whereas ligand-based drug design includes pharmacophore modeling, quantitative structure-activity relationship (QSARs), and artificial intelligence (AI).

CADD can be separated into ligand or hit identification and ligand or hit optimization, with both SBDD and LBDD methods useful in the appropriate context. Database screening methods are often used for hit identification (59) while a number of methods may be used for hit optimization (4, 24, 60). Below we present a collection of methods that may be used for both ligand identification and optimization. Computers have become an important part of every lab and drug discovery or designing processes are no exceptions. Based on that, it designs molecules that bind specifically to the protein according to the lock-and-key principle so they can interact with it.

Different methods employed in the identification of new inhibitors from chemical databases include pharmacophore modeling, quantitative structure-activity relationship (QSAR), molecular docking, quantum mechanics, and statistical learning methods. CADD can be broadly divided into structure-based and ligand-based drug design approaches, both have been widely used in the drug discovery process in the identification of suitable lead molecules. While the structure-based drug design relies on the three-dimensional structure of the target receptor and its active sites to understand the molecular interaction between the receptor and ligand, the ligand based-drug design depends on the knowledge of ligands interacting with the given target receptor [9]. Computer-aided drug design has a large number of success stories and continues to play a vital role in the drug discovery process [10]. In this regard, the approach has been utilized in proposing drug candidates against coronavirus disease 2019 (COVID-19).

The successful applications, limitations and future prospects of this approach have also been discussed. Pharma companies amass collections of compounds for screening in-house, whereas in-stock collections from vendors (see the figure, part a) allow fast (less than 1 week) delivery, contain unique and advanced chemical scaffolds, are easily searchable and are HTS compatible. However, the high cost of handling physical libraries, their slow linear growth, limited size and novelty constrain their applications.

Conversely, interactions of electrons with the nuclei of the compounds should be considered in small systems which require the application of quantum mechanics calculations. Quantum mechanics are based on quantum physics and very accurate electronic properties can be predicted using the appropriate level of theory and basis set. For instance, electron potential maps and frontier molecular orbitals and several parameters related with to them (chemical hardness, softness, ionization potential etc.) can be calculated.

In this process the available information of ligands and their biological activity is used for the development of new potential drug candidates. LBDD is widely used in pharmaceutical research, as more than 50% of approved drugs targeting membrane proteins (for which 3D structures are often not available, such as, GPCR). It is based on the assumption that compounds with similar structural features share common biological activities and interact/inhibit common target molecules [36, 37]. Running such data-rich computationally driven pipelines requires overarching data management tools for drug discovery, many of them being implemented in pharma and academic DDD centres146,147. Building computationally driven pipelines will also help to reveal weak or missing links, in which new approaches and additional data may be needed to generate improved models, thus helping to fill the remaining computational gaps in the DDD pipeline.

Some of the hardest cases are targets with cryptic or shallow pockets that have to open or undergo a substantial induced fit to engage ligand, as often found when targeting allosteric sites, for example, in kinases or GPCRs, or protein–protein interactions in signalling pathways. To answer those questions, we focus on structure-function, dynamics, and pharmacology of the GPCR superfamily, probing it with state-of-the-art structural bioinformatics and molecular modeling tools, and validating the predictions with experimental data from public sources and collaborators. Before we come to our topic of computer-aided drug designing, let's first introduce what is drug discovery. Over the years it has become clear that despite advances made in experimental mutational studies, a quantitative understanding of enzyme catalysis will not be possible without the use of computer modeling approaches. While we believe that electrostatic preorganization is by far the most important catalytic factor, convincing the wider scientific community of this may require the demonstration of effective rational enzyme design. Here we make the point that the main current advances in enzyme design are basically advances in directed evolution and that computer aided enzyme design must involve approaches that can reproduce catalysis in well-defined test cases.

Sunday, April 28, 2024

The Way of the Househusband 2022

way of the house husband

Wedding costs can vary greatly depending on the location. Large metropolitan areas tend to have steeper prices, especially for venues. The average cost of a wedding in Los Angeles is $34,492, which is a bit higher than the 2020 national average of $33,900. Keep in mind that the average costs include elopements and ceremony-only weddings, which skip venues and have much smaller guest numbers. To legally marry in Los Angeles county or any city in the State of California, you will need a California marriage license. When we saw this home, I had told the listing agent, “Oh, I used to live down the street.

Live-Action Way of the House Husband Trailer and Opening Released - GameRant

Live-Action Way of the House Husband Trailer and Opening Released.

Posted: Thu, 07 Apr 2022 07:00:00 GMT [source]

Manga Volumes

way of the house husband

By creating an account, you agree to the Privacy Policy and the Terms and Policies, and to receive email from Rotten Tomatoes and to receive email from the Fandango Media Brands. Gokushufudou or The Way of the House Husband is a comedy seinen manga written and drawn by Kousuke Oono. It is published in English by Viz Media LLC. The first volume is officially available for purchase on September 17th, 2019. An original net animation (ONA) series produced by J.C.Staff was released from April to October 2021 on Netflix. A second season premiered in January 2023.

GokushufudouThe Way of the Househusband

With temperatures in the low to mid-70s and fewer crowds, spring is a comfortable season for walking and visiting outdoor attractions. There’s rarely any precipitation in LA during the springtime, making it ideal for outdoor weddings. Also, hotel rates are likely to have discounts during this time, which is great for traveling guests. City Hall weddings are increasingly popular for affordable, same-day ceremonies. The City Hall is easy to book, LGBTQIA supportive, and can serve as a neutral ground for couples with different religious backgrounds. County RR/CC offers to conduct civil weddings virtually via online appointments.

'I just got an email on my husband’s iPad about the water in his apartment. We live in a house.' UPDATED 5X

I haven't slept so I hope this makes sense. Call them, explain you have a delivery for Mr. OP but the Unit # is missing & you’re under a deadline to deliver, as it’s perishable. There was no unit number on the email but the complex is about 15 minutes away from our house so I went and I drove by. Which I guess might be a little crazy, I know. I didn’t see anything (not like I knew what to expect?) It’s a group of buildings. We’ve got wedding planning advice on everything from save the dates to wedding cakes.

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My husband, who is upstate visiting his mother until Saturday, has next to no cell service so I haven't been able to talk to him about any of this other than saying that the email must have been a 'mix up'. My friend called and got his apartment number from the maintenance man. Both of us went over to the apartment and my friend knocked. A girl answered but didn't answer the door, just the bell camera.

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This is also a season when you can find good flight and hotel deals, which can especially come in handy to catch famous award shows in LA at this time, such as the Grammys. Fall has cooler temperatures in the high-70s and is a great time to find flight and hotel deals when planned. If you prefer to avoid the peak tourist season, a fall wedding might be your best option.

Best Spots for Wedding Photos in Los Angeles

Otherwise he might talk her into thinking you were just a jealous future ex wife stalking his new girlfriend or something. In sugar dating it's pretty common for the allowance and help with rent/bills etc to start pretty early, sometimes after the second date. If he was her sugar daddy then OP might have a financial claim to the marital assets he spent supporting the girlfriend. I am guessing the girlfriend messaged him which is why he knew why you were there. Be sure to login to your bank accounts and if you feel it is necessary take a screenshot and withdrawal half of it into a new account just under your name. I’m not going to get into the exact details of it.

That kind of confrontation is not just "are you having an affair?", there's plenty of other answers OP deserves also. Especially since the first answer really could be anything from "yes, that's my other wife" to "no, that's the daughter my HS gf hid from me for 25 years" and anything in between. Currently, Los Angeles County can only have small private gatherings with a maximum of 15 individuals. Private gatherings must be outdoors with all guests wearing masks and maintaining a 6-foot-distance. If you, your partner, and all other wedding guests are fully vaccinated by your wedding date, you’re free to have an indoor wedding without restrictions.

Starting out

It was an email from an apartment complex that they were going to be temporarily closing down the hot water for repairs, sent from one of those automatic senders that you can’t reply to. With this guide, you and your partner have everything you need to plan the perfect LA wedding. Be sure to check out more expert advice for additional tips and resources on all things wedding. From destination wedding checklists to invites, Zola has everything you need all in one place.

Read the full story, Reddit’s response, and our ultimate takeaways ahead. After disappearing from the underworld, the legendary yakuza known as the "Immortal Dragon" resurfaces — as a fiercely devoted stay-at-home husband. I can also understand she may be under shock with how everything played out.

You will need this to get legally married in Los Angeles county. We did the appraisal and inspection the same day. The one in La Puente, my husband really wanted.

Virtual civil weddings cost $35 in addition to license fees. The L.A County RR/CC distributes marriage licenses. Currently, during the COVID-19 pandemic, you can apply for your marriage license online through the county’s website. Once reopened to the public, you and your partner can apply for a marriage license at one of its seven branch office locations. "OP should go straight to a lawyer and not bother talking to their partner about it first" might be the most stereotypically internet take of all time. Being in touch with a lawyer is not better than confronting him first.

Way of the Househusband Releases Video for In-Anime Series Crimecatch Policure - CBR

Way of the Househusband Releases Video for In-Anime Series Crimecatch Policure.

Posted: Fri, 30 Dec 2022 08:00:00 GMT [source]

It was a one-bath, three-bedroom but had a converted garage. There were 20 people in line to see that particular home, and we had heard that particular house had 36 offers. But they accepted an offer for $100,000 over asking. Tran and her husband, John, 30, started looking to buy a place last year to make space to grow their family.

The Way of the Househusband Wikipedia

way of the house husband

The bank or the escrow company needed the money by a certain time, and the money came in later, so we had to wait an additional one or two days to close because of that, which we weren’t aware of. We realized, OK, well, we have actually a pretty good budget to work with. Buying a house in California has become increasingly hard. The pandemic pushed the market into overdrive as people scrambled for more space.

Read The Way of the Househusband manga

Tran left the Nashville job and came back to Southern California. The Streamable helps you find the best way to stream anything. Follow our daily streaming news, and in-depth reviews on streaming services & devices, and use our tools to find where your favorite content is streaming.

8 anime to watch if you like The Way of the Househusband - Sportskeeda

8 anime to watch if you like The Way of the Househusband.

Posted: Tue, 03 Jan 2023 08:00:00 GMT [source]

The Affair Comes to Light

My friend tried to ask her more questions, she wasn’t giving her any information. The few times the call did pick up the service was so bad you could barely hear anything. So I'm headed upstate to confront him in person. I have a copy of the email, as well as a photo of the apartment, as well as a recording of the girl saying that Adam wasn't there (which is a confirmation to me that she knows him). It was addressed to my husband, with his first and last name.

Advice and support

The maintenance guy didn’t speak English very well so I think he was somewhat confused, but he eventually gave us an apartment number. Call the apartment complex to see if they are shutting down the water to see if its real and then do some more digging. But HMRC says married couples or civil partners can only count one property as their primary residence. Mr Bowen also revealed his daughter let her brother Darren, 46, live at the property.

Since he seems to be good at making lies and playing with women. It's possible he was already preparing his exit plan with her. Once he was ready he would have divorced you and be official with his girlfriend, and try to keep her in the dark about you not being separated while he was seeing her, so she wouldn't know the truth.

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15 Best Anime Characters Voiced By Kenjiro Tsuda.

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My friend said she was there looking for Adam. The girl said that Adam wasn't there but wouldn't give her more information than that (which I get, my friend was just a total stranger at her door). When we left I could see her looking out the apartment window at us. I tried to call my husband a thousand times yesterday and nothing went through.

While you can expect higher hotel rates during this season, it is also a time when several popular summer festivals take place, including LA Pride. Anyone who is ordained in the State of California can officiate your wedding. Acceptable Los Angeles wedding officiants include, but are not limited to, ministers or priests of any religion, commissioners of civil marriages, a California congressperson, or a judge. The most convenient place to find a same-day wedding officiant is City Hall. There are also many same-day wedding officiant services available throughout Los Angeles, such as through wedding planners.

Once you’ve set a wedding date, it’s time to bring in the wedding professionals. Remember, a good rule of thumb is to book venues and other wedding planning vendors at least 12–18 months before your date. There are universal ministries that provide online ordination services, even some within the same-day, to people of all backgrounds, beliefs, and sexual orientations. This allows couples to choose whom they desire to officiate their weddings. Out-of-state and out-of-country marriage officiants can perform marriages in the State of California as long as they are ordained or invested by a denomination. He's clipping coupons, planning penny-saving meals — and taking his job as a househusband very, very seriously.

way of the house husband

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I wish we would have shopped around for mortgages. But I feel like we could have done our due diligence of shopping around versus just going with this Realtor. Tran was counting on a major bonus from a new job she had that required her to move to Nashville — another advantage that helped her save. The couple started looking at condos in L.A. County remotely and went into escrow twice on two different ones.

Bear in mind that activity restrictions during the coronavirus pandemic are constantly evolving and may differ by the area. From weeks up to the official day of your wedding, make sure to follow news and updates from the County of Los Angeles Public Health. Many people underestimate the cost of the home-buying process and owning a home beyond the mortgage. Here are some open house dos, don’ts and red flags — with a handy checklist to remind you what to ask and look out for. Home-scrolling is a special kind of pastime in Southern California.

From its bustling nightlife to the iconic Hollywood sign, Los Angeles is a popular wedding and honeymoon destination all-in-one. Even though this home isn’t perfect, I feel like it was a blessing. I used to be the girl who lived in the apartments across the street, and now I’m the girl who owns the house with the pool. What was frustrating was we had a conversation with our Realtor the night before we had transferred our money to escrow and nothing came up about that. To find out that we were delayed an additional two days was just frustrating because nothing was communicated to us.

They had been renting a house in the San Gabriel Valley and were hoping to land somewhere between there and the Long Beach area, where her parents live. “Messy” doesn’t even begin to cut it for that situation, which is what one woman on Reddit is finding out right now. She agreed to stay with her husband after an affair and an affair baby came to light — but now, somehow, it’s all getting even more complicated. With her husband asking that they take in the affair child (now older), the woman (aka our OP, or the author of the post) responded in a way that has Reddit’s Am I the Asshole?

Infidelity has a way of either making things very messy or painfully clear. For some people, finding out that a partner cheated calls for an immediate break-up, no matter the situation — what we call a dealbreaker. For those who to choose to stay, well, it often takes a lot of work to re-establish that trust and build that bond up again, and even then, the relationship will never be exactly the same. That’s especially true when the affair results in a baby. Please, stop advising me NOT to go talk to my husband about this very serious situation that we are in. However, we have been married for over a decade, we have a family, and a life together.

way of the house husband

The only time you need to involve the lawyer before you involve your partner is when you feel unsafe, or if the partner could potentially hide evidence of their affair based on the confrontation. I don’t have any reason to mistrust my husband other than this weird email that gives me a strange feeling in the pit of my stomach. As well as a general feeling of paranoia that he’s just been…bored with me. I’ve been feeling this way for a little while but he insists I’m imagining it and that he’s happy (I only bought it up to him once, when I was feeling particularly insecure last year). To help you prepare, here is an overview of the logistics and travel details so you get the best experience with your loved ones during your wedding. Summertime in LA is peak tourism season, and also when the city experiences the hottest temperatures of the year.

This last year we focused on cutting spending, cutting costs. And moving for my new job, that’s where I made my money. Tran, a retail buyer, and her husband, an IT supervisor, each earn six-figure incomes.

Ms Rayner is being investigated by police and HMRC over whether she lived at her ex-council house in Vicarage Road, Stockport. So when we closed, the day after, we started painting the entire interior and then we worked on retiling the bedroom floors. And really, those were the only two projects that we wanted to get done right away. We had been saving for about eight years.

14: Back Designs The World of Playing Cards

back of card design

Conversations struck up on the treadmill, at the coffee counter or even on public transit may lead to business opportunities. Make sure you always have a stack of cards in your car, wallet, briefcase or purse. If you want your business card to stand out, non-traditional materials will help you do just that. Designed by Rodrigo Cuberas, this bike garage business card uses cotton paper stock as the base for its stunning, simplistic design. This playing card product design was the most fun I’ve had making something for myself in a long time.

Sweetule Natural History cards

This roofing company’s business card is on-brand, unique and foldable—turning from a 2D card into a 3D slate-tiled, pitched roof. The typography of the card is clean and minimalist, with a single block of neatly justified text. The inside of the card also features Andrew Murray Roofing’s simple, text-less logo, which fits in well with the monochromatic, minimalist style. The simple fold turning the card into a three-dimensional roof keeps the folding-business-card effect from feeling too gimmicky while still elevating the experience for potential customers. If cardboard, plantable paper or plastic weren’t enough, consider using other nontraditional materials for your business cards.

Delta's New Metal Credit Card Is Made From a Retired Boeing 747 Plane - Business Insider

Delta's New Metal Credit Card Is Made From a Retired Boeing 747 Plane.

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Digital Flash Cards - Goodnotes Flash cards - Ipad Flash Cards - Multiplication Flash Cards

The fur idea got dropped early due to production complications (cutting and stitching was too time consuming and messy). What remains are shrink-wrapped decks lovingly placed in various handmade leather pouches. Each pouch also makes an excellent dice container (holds 2 full sets) and can be repurposed to whatever your heart desires. Stay away from “custom playing card” junk like 4 Imprint, Zazzle, and Shutterfly unless all you need is to slap a logo on a deck and care nothing about quality.

Let's Get Growing Blank Card Set of 5

Disregarding the design and layout time (which must be around 100 hours 🙃), here is the cost breakdown for both deck releases, based on my budget of $1000. Increasing awareness and appreciation of the cultural and historical significance of playing cards since 1996. A limited edition art print of the King of Diamonds 1984 woodblock joker. A limited edition art print of the Jack of Hearts 1984 woodblock joker. A limited edition art print of the Jack of Clubs 1984 woodblock joker.

A business card, a functional comb and a musical instrument, this salon’s innovative branding is as unique as it is usable. While it may seem gimmicky, this lightweight plastic business card will still comfortably slide into a wallet or fit in a standard business card holder. This graphic designer’s business card is simple, charming and stands out in a crowd.

Many business card design companies offer lightweight metal or wood options. Both of these are sure to last longer and feel better in the hands of a potential client. This sommelier, or “sommelière” in the traditional French, went for a simple yet elegant business card. Simple, unique and specific, these cards are designed to catch the eye—and possibly the nose, too.

Before saving the file, put each multi-layer illustration into a folder/group in Photoshop and center it. When the artwork looks good, save each card as its own high-resolution flat 300dpi or 600dpi CMYK TIF file (a PNG also works fine, I’m old-fashioned). This is the finished card art that will be imported into our Illustrator deck master file.

Colour doodle deck

Highly original and striking designs by Paco Lobo for the fashion house of the same name. Inglewood Hunting Deck created by Ian Cumpstey, United Kingdom, 2023. Even the smaller firms, Whitaker, Perry and Steer, had decorative backs on some of their cards, most of which seem to have come from Turnhout. Find out what’s new on Freepik and get notified about the latest content updates and feature releases.

Gimmicks can be fun, but unless carefully designed to match your brand, they may just come off tacky or immature. Always focus first and foremost on high-quality prints of well-designed, aesthetically pleasing cards. The line between functional business cards and hilarious gimmicks can be a tough one to find, but even the silliest of business cards can still get the job done. Functional business cards can have serious longevity if your customers can actually use them. Even business cards that aren’t actually cards—for instance, combs, toothbrushes or pens with contact information printed on them—are more likely to be kept around much longer. A less-functional gimmick may be fun for a moment, but may be quickly forgotten.

Vying for “most minimalist business card,” this college-ruled lined notebook paper-inspired card keeps the info short and sweet with a name, title, email, website and phone number. Guaranteed to instill recipients with nostalgia for school days, this graphic designer will surely receive calls for work. This pool cleaning company knows exactly how to get its customers in the door.

back of card design

In this day and age, double-sided business cards give any business a leg-up by being more eye-catching and also easily findable amongst a large stack. Most printing companies make double-sided business cards fairly affordable. The best business card for you is the one that best represents who you are and what you do.

back of card design

The card’s rich 2% back and bonus make it a good flat-rate cash-back card. The card is available exclusively for new and existing Delta SkyMiles Reserve and Reserve Business Card Members from April 25 through June 5, 2024, while supplies last. Found something you love but want to make it even more uniquely you?

Clearly designed to catch an eye across the room, the bright pops of color combined with retro color palettes will certainly trigger nostalgia and charm among certain demographics. The typeface is bold and unique to the point of being memorable, and this photographer and creative director’s brand remains consistent across her website and social media. As long as there are parties, industry events, and networking opportunities, there will be business cards. And it's important that yours isn't thrown to the bottom of the pile because of a lackluster design. Playability and card handling is king, so my budget always starts by choosing the best card stock available.

When this design studio wanted to give their corporate identity a facelift, they turned to fresh card stock in yellow, smokey blue, and azure. Using minimal text against a sophisticated color palette yields sleek results. Designed to resemble a classic take-a-number ticket, this inventive business card was devised for Dutch agency Counter Creatives by designer and art director Valery Overhoff. The compact format and unconventional shape called for a creative use of space, and Overhoff manages to feature multiple typefaces and both vertical and horizontal text. Liber Ludorum playing cards created by Ian Cumpstey in the insular style, United Kingdom, 2019.

Saturday, April 27, 2024

Watch Mickey Mouse Clubhouse TV Show

mickey mouse club house

It was revealed that Mickey and the gang think of the Handy Helpers as helpful friends and not servants. One Handy Helper is usually seen opening the front door for The Sensational Six and their friends. In one episode, the Handy Helpers begin to act crazy and stop working, and Mickey and the gang decide to help out, stating that the Handy Helpers are their friends. It was also revealed that the inner workings of the Handy Helpers come from the Handy Dandy Machine located in the basement underneath the Clubhouse which can be accessed by a down slide. The Mousekedoer is a special machine that runs on a special energy source called "Liquid Light" and is the main power source for Toodles, as revealed in "Mickey's Mousekedoer Adventure". Whenever the Sensational Six are about to set off on a fun adventure or important mission, the Mousekedoer provides them with special Mouseketools that will help them on their mission/adventure.

Episodes

mickey mouse club house

Mickey directly addresses the viewers, inviting them to participate in solving problems. Mickey entertains preschoolers by inviting them to join him and his friends for a date at the Clubhouse. Where the Clubhouse Rocket is kept, situated in the center of the mouse head. Can be accessed via cup car in the main living area or by ladder in the Fanfarea. Should the Liquid Light stop flowing to the Mousekecore (which is basically the heart of the Mousekedoer), the Mousekedoer would start fritzing, give mixed-up Mouseketools, and cause Toodles' screen to glitch.

‘Mickey Mouse Clubhouse’ To Be Revived, As Disney Junior Reveals New Slate Including Shows With Taye Diggs ... - imdb

‘Mickey Mouse Clubhouse’ To Be Revived, As Disney Junior Reveals New Slate Including Shows With Taye Diggs ....

Posted: Thu, 28 Sep 2023 04:00:32 GMT [source]

Mickey's House at Disneyland California

Each visit sees at least one character get into an issue or scenario that must be solved quickly. Mickey could also use the "Picture Puzzle" device to reveal an image that relates to the episode's topic, usually being accompanied by its own song. One of the tools is a "Mystery Mouseketool", which is a surprise tool represented by a question mark that isn't revealed until later in the episode. Toodles lays himself onto the Mousekedoer to download the tools that have been shown on the machine's screen and prepare for Mickey and the gang to use the tools. The episode's main plot then plays as Mickey and his friends search for the solution.

More Walk-Through Attractions at Disneyland

mickey mouse club house

Using early math learning and problem solving skills, he leads kids on an interactive adventure of learning and fun. Watch Mickey Mouse Clubhouse every morning at 8am/7c on Disney Junior on Disney Channel. At the end of every episode, the characters stand in front of the Mousekedoer during the Hot Dog Dance, during which the Mousekedoer twists around to the outside before the characters leave the clubhouse. Mickey Mouse Clubhouse Season 1 is available to watch on Disney Plus. Disney Plus is a streaming platform that provides its audience with access to all of the exclusive Disney content and more, including Frozen 2 and Bluey, among others.

The garage to the Clubhouse, where various tools and equipment can be found. The door to the garage unlocks by unzipping like a zipper, which can be unlocked with keys or with a secret combination. On August 18, 2023, a revival is revealed to be in production and is set to be released sometime in 2025. To log in, use the email address and password you entered when activating your Disney+ account. Disney+ Basic is available with Spectrum TV Select packages or higher at no additional cost. If you have an eligible Spectrum plan with Charter, you can activate your Disney+ Basic account via the activation link in the Plan Details page of your Spectrum account.

X-Men ’97 Creator Reveals Which Story Arc Should Fans Revisit Before Episode 8

Mickey Mouse, Minnie Mouse, Donald Duck, Daisy Duck, Goofy and Pluto, the main stars of the show, interact with the viewers and go on problem-solving adventures. The group has a small, Mickey head-shaped flying super computer named Toodles that acts as an extension of the Mousekedoer and helps the gang with the given problems and carries tools that they might need. The series mainly focuses on interacting with the viewer to simulate problem solving. According to Disney, each episode has the characters help children solve a specific age-appropriate problem using basic skills, such as identifying shapes and counting from one to ten. This show is similar to other shows like Sesame Street, Pee-Wee's Playhouse, Dora the Explorer, and Zoobilee Zoo. The series uses "Disney Junior's common 'whole child' curriculum of cognitive, social and creative learning opportunities."

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Mickey Mouse Clubhouse is an American animated interactive television series for preschoolers. Produced by Disney Television Animation, the series was created by Disney veteran Bobs Gannaway. The series originally aired 125 episodes from May 5, 2006, to November 6, 2016, on the Disney Channel's preschool block, Playhouse Disney (later known as Disney Junior), making it the longest-running original series to air on the block. Mickey entertains a new generation of preschoolers for the first time by inviting them to join him and his favorite friends (Goofy, Donald, Minnie, Daisy & Pluto) for a date at the Clubhouse.

For example, in "Mickey's Silly Problem", when the "Silly switch" turned on, Mickey spoke in rhymes for half of the episode. At the beginning of certain episodes, the Picture Puzzle will light up and play a song, and Mickey and the viewer will have to unscramble a four-piece puzzle to reveal a hidden picture; the picture will be whatever relates to the theme of the episode. Pushing a red button at the center of the unit sets the Picture Puzzle in motion.

Mickey Mouse, walking up a dotted path, greets the viewers and invites them to a playdate at the Clubhouse. He directs viewers to a plot of land where the Clubhouse is, but it's nowhere to be seen. He then remembers and reminds viewers that the Clubhouse can only be summoned using the "magic words" "Meeska, Mooska, Mickey Mouse!" Once said, the Clubhouse forms itself and Mickey and his friends arrive to hang out and play together while the theme song plays.

A successor to this series, Mickey Mouse Mixed-Up Adventures, originally Mickey and the Roadster Racers, debuted on January 15, 2017. It was then succeeded by Mickey Mouse Funhouse, which debuted on August 20, 2021. However, a special episode of this series premiered on July 16, 2021 before the series debut. And with ESPN+, you can stream live sports, thousands of live events, top leagues and tournaments, ESPN+ Originals, and the complete 30 for 30 Library. Plus, get exclusive access to premium articles, fantasy tools, and archives. The Disney+ app is available on mobile devices, web browsers, game consoles, set-top boxes, and smart TVs.

The Mousekedoer usually provides between 3-5 Mouseketools per adventure/mission. On occasion, the Mousekedoer will provide Mouseketools unique for the adventure. For instance, in "Goofy's Thinking Cap," the Mousekedoer provided 4 Mouseke-Think-About-It Tools instead of the usual Mouseketools to help them think up any kind of tool they need. Another example was in "Mickey's Mystery" where each Mouseketool was hidden behind a pictogram to describe the Mouseketool needed for the mission. These tools are transferred into Toodles who would later distribute the tools to the gang when called upon. Besides providing the Mouseketools, the Mousekedoer is also known for many other things.

If the Liquid Light isn't flowing back to the Mousekecore and the Mousekecore isn't started up in time, the Mousekedoer would stop working all together and, in turn, Toodles will shut down permanently. The size of the hands' gloves can also vary depending on the task, from the same size as the famous characters to giant size. In some episodes The Handy Helpers held Mickey or his friends open palm. Usually the Handy Helpers’ gloves are much bigger than the Sensational Six’s hands.

New trailer released for upcoming Mickey Mouse horror movie - FOX 17 West Michigan News

New trailer released for upcoming Mickey Mouse horror movie.

Posted: Tue, 02 Jan 2024 08:00:00 GMT [source]

Visit the Disney+ Help Center to learn more about Disney+ through Spectrum support. Disney Bundle plans include subscriptions to either Disney+ and Hulu, or Disney+, Hulu, and ESPN+, at discounted prices, as compared to the retail price of each subscription when purchased separately. All of these and more now streaming on Disney+, Hulu, and ESPN+ with the Disney Bundle. After the show ended in 2016, it was succeeded by Mickey and the Roadster Racers (later renamed Mickey Mouse Mixed-Up Adventures), which ran from 2017 to 2021, and Mickey Mouse Funhouse, which started in 2021.

Mickey Mouse, Minnie Mouse, Donald Duck, Daisy Duck, Goofy, and Pluto star in the series, taking place at the Clubhouse where most of the events in the series occur. The group also has a small, Mickey-head-shaped, flying super computer named Toodles that acts as an extension of the Mousekedoer and helps the gang with the given problems and carries tools that they might need. Pete, Clarabelle Cow, Ludwig Von Drake, Chip and Dale, Willie the Giant, Butch, Figaro, Humphrey the Bear, Salty the Seal, and Mortimer Mouse have made guest appearances. The series focuses on interacting with the viewer to stimulate problem solving. One of them is a "Mystery Mouseketool" represented by a Question Mark, in which, when the words "Mystery Mouseketool" are said, the question mark changes into the Mouseketool the viewer gets to use.

Another one is a "Mouseke-Think-About-It Tool" represented by a silhouette of Mickey's head with rotating gears, in which characters must think of what to use before telling the Tool "Mouseke-Think-About-It-Tool, we pick the (object)". Once the tools have been shown to Mickey on the Mousekedoer screen, they are quickly downloaded to Toodles, a small, Mickey-head-shaped flying extension of the Mousekedoer. By calling "Oh, Toodles!" Mickey summons him to pop up from where he is hiding and fly up to the screen so the viewer can pick which tool Mickey needs for the current situation.[5][6] Rhymes are used throughout the show.

Disney+ Stream Unlimited Movies and TV Series

mickey mouse club house

Using early math learning and problem solving skills, he leads kids on an interactive adventure of learning and fun. Watch Mickey Mouse Clubhouse every morning at 8am/7c on Disney Junior on Disney Channel. At the end of every episode, the characters stand in front of the Mousekedoer during the Hot Dog Dance, during which the Mousekedoer twists around to the outside before the characters leave the clubhouse. Mickey Mouse Clubhouse Season 1 is available to watch on Disney Plus. Disney Plus is a streaming platform that provides its audience with access to all of the exclusive Disney content and more, including Frozen 2 and Bluey, among others.

mickey mouse club house

Goldie & Bear

You can walk through his living room, den, laundry room and back yard and greet him in his dressing room in the Movie Barn. You can watch a classic cartoon on the television, check out Mickey's collectibles which include a special photo of Mickey with his pal Walt Disney, and don't miss the oversized vegetables in the garden. The 'Mickeyologist' home in Los Angeles could be called the 'Mouse House.' It's filled with games, watched, toys, dolls, even an original Walt Disney business card. When ABC7's George Pennacchio asked Shine, "How many Mickey items do you think you've collected?" Shine had no idea, but he did share a desire to one day share all of his collectibles in some for or fashion. As he put it, "It's better when this kind of Mickey magic and joy is shared." In addition to the Main Living Area, Otherwise known as the “Anywhere Area”, there are other rooms located within the Clubhouse that can be accessed by merely pulling the Anywhere Lever.

Picking Up Friends On The Choo Choo

Once the puzzle is solved, two miniature Handy Helpers will pop up and applaud, and it will sprinkle confetti. Wondering where to watch Mickey Mouse Clubhouse Season 1 online? Mickey Mouse Clubhouse is an interactive children’s television show that originally aired in 2006. The show features the ever-so-enthusiastic Mickey Mouse and his pals Minnie, Goofy, Donald, Daisy, and Pluto, who embark on learning adventures. The Handy Helpers are self-controlled machines that resemble gloves of the famous characters created to do daily jobs such as cooking and cleaning. Not only do they work in the clubhouse, but they can also work anywhere and on anything.

Mickey Mouse Clubhouse

mickey mouse club house

Mickey Mouse Clubhouse is an American animated interactive television series for preschoolers. Produced by Disney Television Animation, the series was created by Disney veteran Bobs Gannaway. The series originally aired 125 episodes from May 5, 2006, to November 6, 2016, on the Disney Channel's preschool block, Playhouse Disney (later known as Disney Junior), making it the longest-running original series to air on the block. Mickey entertains a new generation of preschoolers for the first time by inviting them to join him and his favorite friends (Goofy, Donald, Minnie, Daisy & Pluto) for a date at the Clubhouse.

Mickey Mouse Missing From Disney+, Thousands Demand His Return - Inside the Magic - Inside the Magic

Mickey Mouse Missing From Disney+, Thousands Demand His Return - Inside the Magic.

Posted: Sun, 14 Jan 2024 08:00:00 GMT [source]

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Each visit sees at least one character get into an issue or scenario that must be solved quickly. Mickey could also use the "Picture Puzzle" device to reveal an image that relates to the episode's topic, usually being accompanied by its own song. One of the tools is a "Mystery Mouseketool", which is a surprise tool represented by a question mark that isn't revealed until later in the episode. Toodles lays himself onto the Mousekedoer to download the tools that have been shown on the machine's screen and prepare for Mickey and the gang to use the tools. The episode's main plot then plays as Mickey and his friends search for the solution.

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However, in this incarnation, Mickey's and Minnie's 3D renderings are truer to their original hand-drawn likenesses, in that their ears remain distinct perfect circles regardless of which way their heads are turned. The show features two original songs performed by They Might Be Giants, including the opening theme song and the closing song "The Hot Dog Song", which echoes Mickey's first spoken words in the 1929 short The Karnival Kid. Along with improved animation for the second season, the series transitioned into a widescreen HD format. All the episodes of this series, excluding Mickey's Great Clubhouse Hunt, are available on Disney+.

Such as translating messages, creating a Mousekemap, delivering important items, and even changing color. At the beginning of every episode, Mickey uses the magic words to make the clubhouse appear. The magic words, Meeska Mooska Mickey Mouse, are derived from the Mickey Mouse Club. Should someone say the words incorrectly, the parts of the clubhouse will disconnect and float away, as is evident in one episode.

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For example, in "Mickey's Silly Problem", when the "Silly switch" turned on, Mickey spoke in rhymes for half of the episode. At the beginning of certain episodes, the Picture Puzzle will light up and play a song, and Mickey and the viewer will have to unscramble a four-piece puzzle to reveal a hidden picture; the picture will be whatever relates to the theme of the episode. Pushing a red button at the center of the unit sets the Picture Puzzle in motion.

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When ready to pick a Mouseketool, the gang shouts "Oh, Toodles!" to call Toodles, who pops up from where he is hiding and presents the set on-screen so the viewer can pick which tool Mickey and his friends need for the current situation, which usually works flawlessly. Mickey then directs his friends back to the Clubhouse to perform the Hot Dog Dance while the person with their issue fixed thanks viewers for their help and Toodles returns to his spot on the Mousekedoer, which spins around to the outside to allow everyone to leave. The Clubhouse then disappears as Mickey thanks viewers for their visit. The program was initially announced on March 1, 2005, by Gary Marsh, who is the Executive Vice President of Original Programming and Production for The Walt Disney Company. The characters debuted in CG form in 2003 at the Magic Kingdom attraction Mickey's PhilharMagic, then in the 2004 home video Mickey's Twice Upon a Christmas.

Mickey directly addresses the viewers, inviting them to participate in solving problems. Mickey entertains preschoolers by inviting them to join him and his friends for a date at the Clubhouse. Where the Clubhouse Rocket is kept, situated in the center of the mouse head. Can be accessed via cup car in the main living area or by ladder in the Fanfarea. Should the Liquid Light stop flowing to the Mousekecore (which is basically the heart of the Mousekedoer), the Mousekedoer would start fritzing, give mixed-up Mouseketools, and cause Toodles' screen to glitch.

Mickey Mouse, Minnie Mouse, Donald Duck, Daisy Duck, Goofy, and Pluto star in the series, taking place at the Clubhouse where most of the events in the series occur. The group also has a small, Mickey-head-shaped, flying super computer named Toodles that acts as an extension of the Mousekedoer and helps the gang with the given problems and carries tools that they might need. Pete, Clarabelle Cow, Ludwig Von Drake, Chip and Dale, Willie the Giant, Butch, Figaro, Humphrey the Bear, Salty the Seal, and Mortimer Mouse have made guest appearances. The series focuses on interacting with the viewer to stimulate problem solving. One of them is a "Mystery Mouseketool" represented by a Question Mark, in which, when the words "Mystery Mouseketool" are said, the question mark changes into the Mouseketool the viewer gets to use.

Disney+ is a streaming service where you can watch movies, series, and originals from Disney, Pixar, Marvel, Star Wars, Nat Geo, and more. Here’s how you can watch and stream Mickey Mouse Clubhouse Season 1 via streaming services such as Disney Plus. Specials, such as Mickey's Great Clubhouse Hunt, Road Rally, and A Goofy Fairy Tale (the series finale), have also been released over the course of the series. Wheelchairs should go up the ramp on the right side of the house. Cynics say the entire house is just a dressed-up queue to distract you from the sometimes long wait to meet the world's most famous mouse, but that's just fine with me.

Mickey Mouse, walking up a dotted path, greets the viewers and invites them to a playdate at the Clubhouse. He directs viewers to a plot of land where the Clubhouse is, but it's nowhere to be seen. He then remembers and reminds viewers that the Clubhouse can only be summoned using the "magic words" "Meeska, Mooska, Mickey Mouse!" Once said, the Clubhouse forms itself and Mickey and his friends arrive to hang out and play together while the theme song plays.

The only way to bring them back to its original spot is by touching each individual part of the clubhouse and saying the magic words exactly right and they will fly back to their original location. In another episode, a crystal known as the Crystal Mickey is revealed to be the source of the Clubhouse’s Meeska Mooska Magic. The Clubhouse disappears at the end of every episode once the whole group leaves. The Silly Switch is a large lever that causes something amazing or silly to happen depending on the theme of the episode when pulled,(hence the name "Silly Switch"). The Disney Plus Basic plan allows users to stream the service’s content with ads, while the Premium plan lets users stream with no ads and download content to supported devices. There are also a variety of bundle packages, scaling from Bundle Duo Basic, which pairs Disney Plus with Hulu for $9.99 per month, to the Disney Bundle Trio Premium for $19.99 per month, which bundles Disney Plus, Hulu, and ESPN Plus.

The garage to the Clubhouse, where various tools and equipment can be found. The door to the garage unlocks by unzipping like a zipper, which can be unlocked with keys or with a secret combination. On August 18, 2023, a revival is revealed to be in production and is set to be released sometime in 2025. To log in, use the email address and password you entered when activating your Disney+ account. Disney+ Basic is available with Spectrum TV Select packages or higher at no additional cost. If you have an eligible Spectrum plan with Charter, you can activate your Disney+ Basic account via the activation link in the Plan Details page of your Spectrum account.

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